Since carotene itself is non-toxic, even in large quantities, there is no complications associated with excessive consumption of carotene-rich foods. Numerous ingested substances are rich in carotenoids. There are several terms that are associated with carotenemia and are often used interchangeably. There is evidence to suggest that overuse of beta-carotene supplements on the other hand, is associated with an increase risk of cancer. Canthaxanthin has been used in over-the-counter “tanning pills” in the United States and Europe, but is not currently Food and Drug Administration (FDA)-approved for this purpose in the United States because of its adverse effects. Carotenemia will NOT present with the following symptoms : Picture from Dermatology Atlas courtesy of Samuel Freire da Silva, M.D.

It may take up to several months, however, for this to happen. All are absorbed by passive diffusion from the gastrointestinal tract and are then partially metabolized in the intestinal mucosa and liver to vitamin A. The ‘whites’ of the eyes (sclera) and the inner lining of the mouth are not discolored in carotenemia but may be so in other conditions association with a yellowish tinge of the skin, like jaundice. There are certain diseases that can also contribute to carotenemia. Therefore carotenemia will not lead to vitamin A toxicity (hypervitaminosis A). In most cases, the condition follows prolonged and excessive consumption of carotene-rich foods, such as carrots, squash, and sweet potatoes. This article does not provide medical advice. [1] It is most prominent on the palms of the hand and soles of the feet. Carotenoids are eliminated via sweat, sebum, urine, and gastrointestinal secretions. Find a Physician                            Privacy Policy, Images and Text Policy                Editorial Policy, Information Policy                        Advertising Policy, Financial Disclosure Policy          Cookie Policy, About Us                                        Contact Us. This is known as carotenemia and the carotene is distributed throughout the body. Carotenemia is a harmless condition and will ease with just dietary change alone. It tends to be more common in the restricting subtype of this disease, and is associated with numerous other dermatologic manifestations, such as brittle hair and nails, lanugo-like body hair, and xerosis. It is not so in carotenemia. First and foremost Carotenemia is a skin condition whereas jaundice is not a condition itself, but is a sign of a failing liver or gallbladder. These high doses of beta carotene have been found to be harmless in studies, though cosmetically displeasing to some. This article on Epainassist.com has been reviewed by a medical professional, as well as checked for facts, to assure the readers the best possible accuracy. Liver function test (LFT) which is usually normal in carotenemia. Increased serum lipids also cause hypercarotenemia because there are increased circulating lipoproteins that contain bound carotenoids. Carotene deposition occurs in various tissues. These dietary measures are sufficient for primary carotenemia. There is no treatment that is necessary for carotenemia. If the sclera and inner lining of the mouth are not discolored, then a preliminary diagnosis of carotenemia may be made. It is a harmless condition that resolves on its own without the need for any medication.

One of the common forms in the human diet, beta-carotene, is converted to vitamin A. Diabetes, hypothyroidism, and liver and kidney disease may alter carotene levels in the body and lead to physical symptoms. Although it can occur in any age group, it is more commonly seen in young children and vegetarians in particular. Carotene can cause a discoloration of the skin when present in large amounts within the body. It is important to note that jaundice describes a clinical presentation and is not a disease on its own. Carrots are by the far the most common cause. Carotene is not toxic to humans and is part of a healthy diet. Carotenemia is a harmless condition and will ease with just dietary change alone.